InterviewHack.ai
Start free
Jobs / Substrate Bio

Member of Technical Staff, Intelligence

Substrate Bio·Londonmid

In short

  • →Analizar y transformar datos de ensayos biológicos con rigor estadístico y calidad.
  • →Construir pipelines de ML y análisis de datos con trazabilidad total (secuencia, muestra, placa, bien).
  • →Diseñar visualizaciones claras que muestren incertidumbre, calidad y efectos de lotes.

Conocimiento en inglés técnico para revisar documentación y colaborar con equipo global.

Apply on company site ↗Share on WhatsApp
✓ Free to start✓ Runs in your browser✓ First dossier, no card✓ Ready in ~1 minute

In ~1 minute you get: who interviews you, the likely questions answered from your CV, and your CV tailored to this job. Your first dossier is free.

The questions they'll ask you

1. ¿Cómo validarías un conjunto de datos de ensayo si llega con una placa mal etiquetada?

2. Dado un conjunto de réplicas de un experimento, ¿cómo decidirías si aceptar o rechazar el resultado?

3. ¿Qué métricas incluirías en una visualización de EC50 para que sea interpretada con confianza por un científico?

🔒 +7 more questions

No card. Upload your resume and the full dossier is ready in ~1 minute.

🎧Land the interview? Bring the copilot. Our free extension listens to the live interview and flashes 3-4-word anchors from your resume and prep — glance, connect, talk. Get the extension →

💵 USD · Remote · No visa

Not finding what you want? Try Micro1

Micro1 places engineers directly at US companies paying in USD. One vetting, multiple offers — no cold applying.

Get matched by Micro1 →
📬Jobs picked for YOUR resume, every morning on WhatsApp. Free: text “vacantes” and the bot sends your daily matches. Subscribe →

What they ask for

  • ✓Experiencia con datos experimentales biológicos reales y desordenados.
  • ✓Capacidad para escribir código reproducible y confiable que otros usen.
  • ✓Conocimiento en estadística aplicada: DISEÑO EXPERIMENTAL, CV, Z′, valores atípicos.
  • ✓Habilidades en análisis de curvas (EC50/IC50) con normalización robusta.
  • ✓Experiencia con datos de SPR, BLI, HPLC o nanoDSF.
  • ✓Capacidad de detectar efectos de placa, lote y desviaciones temporales (control charts).

Don't tick every box? That's normal — your free dossier shows your gaps and how to cover them in the interview.

PythonRSQLGitJupyterLinuxPandasNumPyScikit-learnStatsmodels

Who should you write to at Substrate Bio?

Your free dossier identifies the people who'd interview you — their background, what they value, and how to reach out so you stand out before applying.

LOCATION: King’s Cross, London · PATTERN: Hybrid, with regular time in the lab The opportunity We’re a stealth startup in AI and bio, building infrastructure for data generation. The team is small and elite, the problems are hard, and the foundations are being laid right now. You’d help write them from the first line, with real ownership and a direct line to the founders. This role builds our analysis from the start. Every result leaves an instrument as a trace or a vendor file, and it has to become a value someone can rely on, linked back to the sequence and sample it came from. That means fitting it properly, checking it against controls, catching the plate or reagent lot that drifted, and showing the evidence. Someone has to own that work. That is this role. About us AI for biology has a data problem. The data that matters most doesn’t exist yet, so we’re building the infrastructure to produce it, with quality and traceability built in from day one. We’re in stealth and heads-down on execution. We’ll share more about what we’re building once you’ve spoken with the team. The role You will join the intelligence team and own the analysis of our assay data, and the data and ML infrastructure it runs on, from the point the data has been captured to the result that gets delivered. You will work most closely with the protein characterisation scientists who run the assays, and with the software team, who get data out of the instruments and own the platform it lives on. You build on top of that platform, and you own the quality of the analysis that runs on it. The role is part data engineer and part biostatistician, and all of the data is biological. Much of it is building the analysis and ML pipelines that run on our captured data, and the statistics inside them. The rest is presenting those results clearly, with the statistics that matter, such as uncertainty and QC, shown in a form they can understand. The value is in doing that carefully, in code that behaves the same way on every run. What you will own ● Analysis and ML pipelines that turn captured assay and sequence data into consistent, versioned datasets, linked to the sequence, sample, plate and well each result came from, built with the software team who own data capture. ● Data validation before any analysis runs, catching a mislabelled plate, a swapped sample or a missing well. ● Sequence-level bioinformatics, such as computing the properties of each protein sequence and checking constructs for problems before the DNA is ordered. ● Biostatistics for experimental data: experimental design, replicates and controls, error propagation, outlier handling, and assay acceptance criteria, such as CV across replicates, Z′ for plate assays, and reference standards staying within range. ● Curve fitting, including dose-response (EC50 and IC50) with sound normalisation and fits to SPR, BLI, HPLC and nanoDSF traces, with a measure of confidence on each fitted parameter and automated QC that sends doubtful fits to a person. ● Detection of plate, lot and batch effects across a dataset before it is delivered, and control charting of reference standards so drift shows up over weeks as well as within a run. ● The data visualisation that accompanies each delivered result, showing it with its uncertainty, QC and batch structure, so anyone can understand and check it without asking us. Who you are You have worked with messy experimental data and built things other people relied on. That might have been in a biotech or pharma team, an academic lab, a core facility, or a data-heavy field outside biology where you have since picked up the biology. Nobody arrives with every part of this role. If you are strong in most of it and quick to learn the rest, we want to hear from you. You are happy to get your hands dirty on the data. Much of the job is careful, repeated work on real instrument output, and we want someone who takes pride in doing that well.

Looking for something similar?

Leave your email and we'll alert you when matching jobs appear.

Don't apply unprepared

We research who's interviewing you, tailor your CV and rehearse you live — first one free.

InterviewHack.ai

Prepare for the exact interview: who's interviewing you, a tailored CV, and a real coach.

Product

JobsCompanies hiringAll free toolsResume verdict (Jev)Free cover letterInterview questions by roleTechnical assessment simulator"Tell me about yourself" answerFree ATS checkerInterview-English checkSalary checkSalary negotiation scriptFree STAR answerLinkedIn headline + AboutLATAM salary reportFree coursesBlogTailored CVSpoken practicePricingAffiliates — 30%

Remote jobs

ReactPythonFull-StackLATAMArgentinaMexicoSee all →

Prepare

Spoken practiceFrontendBackendAI EngineerBy companySell with your CV

Company

For employersAboutContactPrivacyTerms

© 2026 InterviewHack.ai · Your CV is yours. Never used to train anything. · A product of IA-PTY

Similar open roles

Member of Scientific Staff, Cell Line Development

Substrate Bio · London

→

Member of Technical Staff, Intelligence - Functoional Genomics

Substrate Bio · London

→

Protein Production Scientist, Biologics

Substrate Bio · London

→

Member of Scientific Staff, Computational Chemistry

Substrate Bio · London

→